๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A guide to drug discovery: Predicting therapeutic value in the lead optimization phase of drug discovery

โœ Scribed by Kenakin, Terry

Book ID
109949251
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
932 KB
Volume
2
Category
Article
ISSN
1474-1776

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

A priori prediction of tissue:plasma par
A priori prediction of tissue:plasma partition coefficients of drugs to facilitate the use of physiologically-based pharmacokinetic models in drug discovery
โœ Patrick Poulin; Frank-Peter Theil ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 374 KB ๐Ÿ‘ 3 views

The tissue:plasma (P t:p ) partition coefficients (PCs) are important drugspecific input parameters in physiologically based pharmacokinetic (PBPK) models used to estimate the disposition of drugs in biota. Until now the use of PBPK models in early stages of the drug discovery process was not possib