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A green and efficient synthesis of 3,3′-arylidenebis[4-hydroxy-6-methyl-2(1H)-3-pyridinone]s in water under microwave irradiation

✍ Scribed by Feng Shi; Longji Cao; Ning Ma; Ge Zhang; Rongshun Chen; Yajie Zhang; Shujiang Tu

Publisher
Journal of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
71 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

magnified image

A series of 3,3′‐arylidenebis[4‐hydroxy‐6‐methyl‐2(1__H__)‐3‐pyridinone]s were synthesized via three‐component reactions of aromatic aldehydes, 4‐hydroxy‐6‐methyl‐2__H__‐pyran‐2‐one, and ammonium acetate in water under microwave irradiation. This method has the advantages of environmental friendliness, short reaction time, high yields, and easy operation. This efficient synthesis not only offers an economical and green synthetic strategy to this class of significant compounds but also enriches the investigations on microwave‐assisted synthesis in water. J. Heterocyclic Chem., (2010).

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