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A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands

✍ Scribed by Evi Kostenis

Book ID
113845552
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
355 KB
Volume
102
Category
Article
ISSN
0163-7258

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Allosteric receptor ligands bind to a recognition site that is distinct from the binding site of the endogenous messenger molecule. As a consequence, allosteric agents may attach to receptors that are already transmitter-bound. Ternary complex formation opens an avenue to qualitatively new drug acti