Recent advances in the various genome-sequencing projects have opened the floodgates to thousands of protein sequences that are possibly new targets for drug discovery. [1] Accordingly, computer techniques are required for the reliable prediction of protein structures accurate enough to serve as a p
โฆ LIBER โฆ
A Virtual Screen for Diverse Ligands: Discovery of Selective G Protein-Coupled Receptor Antagonists
โ Scribed by Engel, Stanislav; Skoumbourdis, Amanda P.; Childress, John; Neumann, Susanne; Deschamps, Jeffrey R.; Thomas, Craig J.; Colson, Anny-Odile; Costanzi, Stefano; Gershengorn, Marvin C.
- Book ID
- 111924504
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 820 KB
- Volume
- 130
- Category
- Article
- ISSN
- 0002-7863
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## Abstract The use of proteinโligand interaction information has been reported to improve and optimize the docking results in virtual screening experiments. Here we propose an improved weightedโresidue profile based method to profile the proteinโligand interactions based on the available dataset o
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