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A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q

✍ Scribed by J. A. HEIT; S. M. ARMASU; Y. W. ASMANN; J. M. CUNNINGHAM; M. E. MATSUMOTO; T. M. PETTERSON; M. DE ANDRADE


Book ID
117961553
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
471 KB
Volume
10
Category
Article
ISSN
1538-7933

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✍ van Heel, David A; Franke, Lude; Hunt, Karen A; Gwilliam, Rhian; Zhernakova, Ale πŸ“‚ Article πŸ“… 2007 πŸ› Nature Publishing Group 🌐 English βš– 211 KB

We tested 310,605 SNPs for association in 778 individuals with celiac disease and 1,422 controls. Outside the HLA region, the most significant finding (rs13119723; P ΒΌ 2.0 Γ‚ 10 -7 ) was in the KIAA1109-TENR-IL2-IL21 linkage disequilibrium block. We independently confirmed association in two further