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A genome scan localizes five non–MHC loci controlling collagen–induced arthritis in rats

✍ Scribed by Remmers, Elaine F.; Longman, Ryan E.; Du, Ying; O'Hare, Ann; Cannon, Grant W.; Griffiths, Marie M.; Wilder, Ronald L.


Book ID
109917954
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
369 KB
Volume
14
Category
Article
ISSN
1061-4036

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Objective. To identify novel non-major histocompatibility complex (non-MHC) genetic loci controlling the severity of homologous rat type I1 collagen-induced arthritis (CIA). Methods. We conducted a genome-wide scan to identify CLA regulatory quantitative trait loci (QTL) in an F, cross between DA (