## Abstract The age of onset of Huntington's disease (HD) is inversely correlated with the CAG length in the HD gene. The CAG repeat length accounts for 70% of the variability in HD age of onset. However, 90% of individuals worldwide with expanded alleles possess between 40 and 50 CAG repeat length
A Genome Scan for Modifiers of Age at Onset in Huntington Disease: The HD MAPS Study
✍ Scribed by Jian-Liang Li; Michael R. Hayden; Elisabeth W. Almqvist; Ryan R. Brinkman; Alexandra Durr; Catherine Dodé; Patrick J. Morrison; Oksana Suchowersky; Christopher A. Ross; Russell L. Margolis; Adam Rosenblatt; Estrella Gómez-Tortosa; David Mayo Cabrero; Andrea Novelletto; Marina Frontali; Martha Nance; Ronald J.A. Trent; Elizabeth McCusker; Randi Jones; Jane S. Paulsen; Madeline Harrison; Andrea Zanko; Ruth K. Abramson; Ana L. Russ; Beth Knowlton; Luc Djoussé; Jayalakshmi S. Mysore; Suzanne Tariot; Michael F. Gusella; Vanessa C. Wheeler; Larry D. Atwood; L. Adrienne Cupples; Marie Saint-Hilaire; Jang-Ho J. Cha; Steven M. Hersch; Walter J. Koroshetz; James F. Gusella; Marcy E. MacDonald; Richard H. Myers
- Book ID
- 117854287
- Publisher
- American Society of Human Genetics
- Year
- 2003
- Tongue
- English
- Weight
- 593 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/378133
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES