𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Genetic analysis of candidate genes modifying the age-at-onset in Huntington’s disease

✍ Scribed by Silke Metzger; Peter Bauer; Jürgen Tomiuk; Franco Laccone; Stefano DiDonato; Cinzia Gellera; Caterina Mariotti; Herwig W. Lange; Helga Weirich-Schwaiger; Gregor K. Wenning; Klaus Seppi; Bela Melegh; Viktoria Havasi; Laszlo Balikó; Stefan Wieczorek; Jacek Zaremba; Dorota Hoffman-Zacharska; Anna Sulek; A. Nazli Basak; Esra Soydan; Jana Zidovska; Vera Kebrdlova; Massimo Pandolfo; Pascale Ribaï; Ludovit Kadasi; Marta Kvasnicova; Bernhard H. F. Weber; Friedmar Kreuz; Matthias Dose; Manfred Stuhrmann; Olaf Riess


Publisher
Springer
Year
2006
Tongue
English
Weight
317 KB
Volume
120
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Genomewide linkage scan reveals novel lo
✍ Javier Gayán; Denise Brocklebank; J. Michael Andresen; Gorka Alkorta-Aranburu; M 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 189 KB

## Abstract The age of onset of Huntington's disease (HD) is inversely correlated with the CAG length in the HD gene. The CAG repeat length accounts for 70% of the variability in HD age of onset. However, 90% of individuals worldwide with expanded alleles possess between 40 and 50 CAG repeat length

Family and molecular data for a fine ana
✍ Squitieri, F. ;Sabbadini, G. ;Mandich, P. ;Gellera, C. ;Di Maria, E. ;Bellone, E 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB 👁 2 views

We analyzed the data on age at onset and CAG size of 319 patients clinically diagnosed with Huntington disease (HD) and 86 presymptomatic subjects recorded by four Italian Centers over the last 14 years. To overcome the problem of different CAG numbers found in each subject, also in the same family,