Seven polymorphic markers identified by polymerase chain reaction (PCR) amplification, including markers for six genes--DRD1L (dopamine receptor, D1-like-2), GLUKA (glucokinase), PF4 (platelet factor 4), ALB (albumin), AFP (alpha-fetoprotein), and BSP (bone sialoprotein)--and one anonymous locus (D1
A genetic linkage map of rat Chromosome 5 reveals extensive linkage conservation with mouse Chromosome 4
โ Scribed by E. Kobayashi; M. Tachibana; H. Ikadai; T. Kunieda
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 306 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0938-8990
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โฆ Synopsis
Linkages among three biochemical loci (Aco1, Ahd2, and Mup1) and four microsatellite loci (A8, Glut1, Jun, and Pnd) were determined to construct a linkage map of rat Chromosome (Chr) 5. Consequently, an extensive linkage map on rat Chr 5 was constructed with the following gene order: A8-Aco1-Mup1-Jun-Glut1-Ahd2-Pnd. In this linkage map, the Jun and A8 loci are newly placed, and two previously reported linkage groups on rat Chr 5 are connected by the Jun locus. The linkage map indicates an extensive linkage conservation between the loci on rat Chr 5 and those on mouse Chr 4.
๐ SIMILAR VOLUMES
Seven polymorphic markers comprising a single linkage group were assigned to rat Chromosome (Chr) 5 by linkage analysis of the progeny of an Fz intercross of Fischer (F344/N) and Lewis (LEW/N) inbred rats. Three genes, oL-L-fucosidase 1 (FUCA1), mitochondrial superoxide dismutase (SOD2), and glucose