A generic static headspace gas chromatography method for determination of residual solvents in drug substance
✍ Scribed by Chang Cheng; Shaorong Liu; Bradford J. Mueller; Zimeng Yan
- Book ID
- 108094279
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 541 KB
- Volume
- 1217
- Category
- Article
- ISSN
- 1873-3778
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## Abstract Static headspace (HS) sampling has been commonly used to test for volatile organic chemicals, usually referred to as residual solvents (RS) in pharmaceuticals. If the sample is not soluble in water, organic solvents are used. However, these seriously reduce the sensitivity in the determ
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