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A general synthesis of novel conformationally restricted arginine side-chain mimetics

✍ Scribed by Lucija P Mašič; Danijel Kikelj

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
105 KB
Volume
41
Category
Article
ISSN
0040-4039

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Abslrart: The synthesis of a new, conformationally restrained a~log of tryptoghan, 1,2,3,4ktrahydtv-2-ami-2-mrboxy\_cyflopentfbJindole (5) is descrhd. The key step involzm the BF3-Et,0 catalyzed intramolecular cycl&atian of adinoketone 2b into the lt3,4tetrahydro\_~~ (3). Conformationally restricted