A one-pot three-component reaction to ac
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F. Anthony Romero; Remond Moningka
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Article
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2010
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Elsevier Science
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French
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A novel and expeditious method to access 1-alkyl-2-aryl-5-nitrobenzimidazoles has been developed. Enlisting solvent-free conditions, 2-fluoro-5-nitroaniline, a primary amine, and substituted aldehyde were melted together in one-pot to generate a variety of 1-alkyl-2-aryl-5-nitrobenzimidazoles.