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A general method for the synthesis of chiral multifunctional chain compounds incorporating pentitol fragments

✍ Scribed by Pikul, Stanislaw; Raczko, Jerzy; Ankner, Kjell; Jurczak, Janusz

Book ID
120470335
Publisher
American Chemical Society
Year
1987
Tongue
English
Weight
973 KB
Volume
109
Category
Article
ISSN
0002-7863

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πŸ“œ SIMILAR VOLUMES

General method for the synthesis of cycl
General method for the synthesis of cyclic peptidomimetic compounds
✍ Michael A Walker; Timothy Johnson πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 82 KB

A number of cyclic peptides, wherein the i and i+1 residue side chains are joined by an alkyl linker and a Weinreb amide is present at the C-terminus, were synthesized. Using LiCl to solubilize these peptides in THF the C-terminus can be readily converted to an activated carbonyl such as an aldehyde