A general method for the synthesis of 1-alkyl-,1-aralkyl, and 1-aryl-5,5-diphenylhydantoins and -glycocyamidines
✍ Scribed by Gy. Simig; K. Lempert
- Book ID
- 104242908
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 115 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract Successful syntheses of 2,4‐dichlorophenyl 2‐(1‐methyl‐5‐imidazolyl)ethyl and 2,4‐dichlorophenyl 3‐(1‐methyl‐5‐imidazolyl)propyl ketones are described. In addition, syntheses of 2,4‐dichlorophenyl and 4‐chlorophenyl 3‐(1‐methyl‐1__H__‐5‐tetrazolyl)propyl ketones are reported.
## Abstract 1‐(Aralkyl/aryl)‐3‐(alkyyaralkyl)‐5‐aroyl‐1,2,3,4‐tetrahydropyrimidines (**2a‐c**) have been synthesized by dethiomethylation of 5‐aroyl‐6‐methylthio‐1,2,3,4‐tetrahydropyrimidines (**1a‐c**). An alternative one‐pot synthetic strategy has been developed for the title compounds **2a‐t** b
## Abstract A general method is described for the synthesis of 1‐aryl‐2‐alkyl‐1,4,5,6‐tetrahydropyrimidines 1, by cyclization of __N__‐acyl‐__N__′‐aryltrimethylenediamines 2 with trimethylsilyl polyphosphate. Precursors 2 were obtained by aminolysis of the corresponding __N__‐(3‐bromopropyl)amides