✦ LIBER ✦

A general method for the dereplication of flavonoid glycosides utilizing high performance liquid chromatography/mass spectrometric analysis

✍ Scribed by Howard L. Constant; Karla Slowing; James G. Graham; John M. Pezzuto; Geoffrey A. Cordell; Christopher W. W. Beecher

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 103 KB
Volume: 8
Category: Article
ISSN: 0958-0344
DOI: 10.1002/(sici)1099-1565(199707)8:4<176::aid-pca351>3.0.co;2-k

No coin nor oath required. For personal study only.

✦ Synopsis

Using high performance liquid chromatography-electrospray mass spectrometry a method was developed to separate flavonoids and flavonoid glycosides and to obtain molecular weight information. Collision-induced dissociation was then used to obtain the molecular masses of the flavonoid aglycones. Thus, the mass of a flavonoid glycoside and its aglycone can now be determined in a mixture, and it is not necessary to isolate the components. An aqueous extract of Eugenia jambos L. was used to demonstrate the utility of the technique in analysing extracts for flavonoid glycosides.

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