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A GENERAL, HIGHLY EFFICIENT SYNTHESIS OF ACETYL AMINO ACID ETHYL ESTERS

✍ Scribed by Dymicky, M.


Book ID
127219954
Publisher
Taylor and Francis Group
Year
1980
Tongue
English
Weight
258 KB
Volume
12
Category
Article
ISSN
0030-4948

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Mono-N-ethylated h-amino acid esters are obtained in high yields using reductive amination procedures. Formation of imine is achieved by excess of acetaldehyde, followed by removal of acetaldehyde and reduction by NaBH(OAc) 3 . The elaborated one-pot synthesis allows for the efficient synthesis of s