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A gas chromatographie assay for medazepam and its major metabolites in plasma

✍ Scribed by E.S. Baird; D.M. Hailey; Susan Malcolm

Book ID
118872230
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
325 KB
Volume
48
Category
Article
ISSN
0009-8981

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## Abstract A sensitive gas liquid chromatographic (GLC) assay was developed for plasma determinations of 8‐chloro‐6‐(2β€² ‐fluorophenyl)‐1‐methyl‐4__H__‐imidazo[1,5 Ξ±][1,4]benzodiazepine (compound I) and its hydroxymethylimidazo metabolite (compound II). The internal standards used were 8‐chloro‐6‐(