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A Gadolinium Complex Confined in Silica Nanoparticles as a Highly Efficient T 1 / T 2 MRI Contrast Agent

✍ Scribed by Wartenberg, Nicolas; Fries, Pascal; Raccurt, Olivier; Guillermo, Armel; Imbert, Daniel; Mazzanti, Marinella

Book ID: 120362106
Publisher: John Wiley and Sons
Year: 2013
Tongue: English
Weight: 305 KB
Volume: 19
Category: Article
ISSN: 0947-6539
DOI: 10.1002/chem.201300635

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## Abstract Iron–dextran (1 mmol Fe/kg) was used as an intravascular, paramagnetic contrast agent in rat and cat brain in conventional spin‐echo T2‐weighted (TR 2800/TE 100) ^1^H magnetic resonance imaging. The resulting images displayed differential decreases (30–50%) in intensity whose pattern wa