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In vivo stability and excretion of gadodiamide (GdDTPA-BMA), a hydrophilic gadolinium complex used as a contrast enhancing agent for magnetic resonance imaging

✍ Scribed by P. T. Normann; P. A. Hals


Book ID
113006827
Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
664 KB
Volume
20
Category
Article
ISSN
0378-7966

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✍ Gabriele Schuhmann-Giampieri; Heribert Schitt-Willich; Thomas Frenzel πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 735 KB

The introduction of a lipophilic moiety into the gadolinium chelate Gd-DTPA (dimeglumine gadopentetate, Magnevist) yielded Gd-EOB-DTPA (short form), which has potential as a magnetic resonance contrast agent for liver mass screening. The pharmacokinetics of Gd-EOB-DTPA in rats is nonlinear because a