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A further investigation of alcohol preference in the laboratory rat induced by hypothalamic stimulation

✍ Scribed by Z. Amit; Muriel H. Stern

Publisher
Springer
Year
1971
Tongue
English
Weight
535 KB
Volume
21
Category
Article
ISSN
0033-3158

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## Abstract The effect of obesity induced by a high‐fat diet on the pharmacokinetics (PK) of nelfinavir (NFV) was investigated, focusing on the change of distribution and elimination caused by dyslipidemia and hepatic steatosis. The plasma unbound fraction (__f__~u~) of NFV in obese rats (0.61Β±0.0