A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis
β Scribed by Baugh, J A; Chitnis, S; Donnelly, S C; Monteiro, J; Lin, X; Plant, B J; Wolfe, F; Gregersen, P K; Bucala, R
- Book ID
- 110037399
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 160 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1466-4879
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π SIMILAR VOLUMES
## Abstract ## Objective To establish linkage and replicate the association of macrophage migration inhibitory factor (MIF) with juvenile idiopathic arthritis (JIA). ## Methods Three hundred twentyβone Caucasian simplex families from the UK were genotyped for polymorphisms of MIF using SNaPshot
Background: Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with increased expression in inflammatory bowel disease. The aim of the study was to analyze the role of the MIF -173G/C single nucleotide polymorphism in Crohn's disease (CD). ## Methods: Using restriction fra