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Mutation screening of the macrophage migration inhibitory factor gene: Positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis

✍ Scribed by Rachelle Donn; Zaynab Alourfi; Fabrizio De Benedetti; Cristina Meazza; Eleftheria Zeggini; Mark Lunt; Adam Stevens; Emma Shelley; Rebecca Lamb; the British Paediatric Rheumatology Study Group; William E. R. Ollier; Wendy Thomson; David Ray

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
93 KB
Volume
46
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To establish linkage and replicate the association of macrophage migration inhibitory factor (MIF) with juvenile idiopathic arthritis (JIA). ## Methods Three hundred twenty‐one Caucasian simplex families from the UK were genotyped for polymorphisms of MIF using SNaPshot

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## Objective. To determine if polymorphisms of the macrophage migration inhibitory factor (MIF) gene are associated with systemic-onset juvenile idiopathic arthritis (JIA). Methods. Denaturing high-performance liquid chromatography was used to screen for the MIF gene in 32 healthy Caucasian subjec