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A four-step domino Knoevenagel–hetero-Diels–Alder reaction

✍ Scribed by Bryhas, Andriy O.; Matiychuk, Vasyl S.; Lis, Tadeusz; Kinzhybalo, Vasyl; Smalius, Victor V.; Obushak, Mykola D.

Book ID
120938015
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
363 KB
Volume
54
Category
Article
ISSN
0040-4039

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Various novel 3,5a,6,11b-tetrahydro-2H,5H-chromeno[4 0 ,3 0 :4,5]thiopyrano [2,3-d][1,3]thiazol-2-ones were synthesized in 60-80% yields via domino-Knoevenagel-hetero-Diels-Alder reactions of 4-thioxo-1,3thiazolidin-2-one with 3,7-dimethyl-6-octenal, 2-allyloxybenzaldehydes and 2-formylphenyl (E)-3a