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A new three-step domino Knoevenagel–hetero-Diels–Alder oxidation reaction

✍ Scribed by Andriy O. Bryhas; Yuri I. Horak; Yuri V. Ostapiuk; Mykola D. Obushak; Vasyl S. Matiychuk

Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
913 KB
Volume
52
Category
Article
ISSN
0040-4039

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Various novel 3,5a,6,11b-tetrahydro-2H,5H-chromeno[4 0 ,3 0 :4,5]thiopyrano [2,3-d][1,3]thiazol-2-ones were synthesized in 60-80% yields via domino-Knoevenagel-hetero-Diels-Alder reactions of 4-thioxo-1,3thiazolidin-2-one with 3,7-dimethyl-6-octenal, 2-allyloxybenzaldehydes and 2-formylphenyl (E)-3a