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A formal convergent synthesis of (+)-trans-solamin

โœ Scribed by Sadagopan Raghavan; S. Ganapathy Subramanian; K.A. Tony

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
126 KB
Volume
49
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

A formal convergent synthesis of solamin is disclosed. The synthetic strategy exploits the potential of the sulfinyl group as an auxiliary, nucleophile and in C-C bond formation. The synthetic route can be adapted to the synthesis of stereoisomers of solamin, analogs with variable carbon side chains, and other members of mono-THF acetogenins.

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