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A Fine-Scale Linkage-Disequilibrium Measure Based on Length of Haplotype Sharing

✍ Scribed by Yan Wang; Lue Ping Zhao; Sandrine Dudoit


Book ID
117854784
Publisher
American Society of Human Genetics
Year
2006
Tongue
English
Weight
613 KB
Volume
78
Category
Article
ISSN
0002-9297

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## Abstract Single nucleotide polymorphisms (SNPs) are important markers to investigate genetic heterogeneity of population and to perform linkage disequilibrium (LD) mapping. We propose a new method, Ξ¨, to express frequency of 2 haplotypes for __N~s~__ di‐allelic SNPs. Using the new expression of