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Assessment of Linkage Disequilibrium by the Decay of Haplotype Sharing, with Application to Fine-Scale Genetic Mapping

โœ Scribed by Mary Sara McPeek; Andrew Strahs


Book ID
117852964
Publisher
American Society of Human Genetics
Year
1999
Tongue
English
Weight
268 KB
Volume
65
Category
Article
ISSN
0002-9297

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Multilocus linkage disequilibrium mappin
โœ Jian Zhang; Daniel Schneider; Carole Ober; Mary Sara McPeek ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 176 KB

We consider the problem of multilocus linkage disequilibrium (LD) mapping of a trait-associated variant from case-control samples in which some individuals may be related. Our method, which we call DHS-R, is an extension of the decay of haplotype sharing (DHS) method of McPeek and Strahs and Strahs