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A Fatal Intoxication from Ingestion of 2-Methyl-4-Chlorophenoxyacetic Acid (MCPA)

✍ Scribed by Takayasu, T.; Hayashi, T.; Ishida, Y.; Nosaka, M.; Mizunuma, S.; Miyashita, T.; Kawaguchi, M.; Kimura, A.; Kondo, T.


Book ID
125477098
Publisher
Preston Publications
Year
2008
Tongue
English
Weight
441 KB
Volume
32
Category
Article
ISSN
0146-4760

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Renal handling of 2-methyl-4-chloropheno
✍ Helmut BrΓ€unlich; Heike Bernhardt; Ingo Bernhardt πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 379 KB

Following i.p. administration of various doses of 2-methyl-4-chlorophenoxyacetic acid (MCPA), ca. 50% is excreted during a 5-h diuresis experiment. After i.p. administration of MCPA, virtually no distribution occurs (Vre, = 18% of the body weight). Renal excretion of MCPA can be accelerated by inhib