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A fast and mild method for the nitration of aromatic rings

✍ Scribed by Radoslaw R Bak; Andrew J Smallridge

Book ID
104231433
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
50 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

The use of N 2 O 5 and a Fe(III) catalyst for the nitration of aromatic rings is described. This methodology is compatible with most functional groups and results in near quantitative yields in 4 min. The reaction conditions are non-oxidising: benzaldehyde and benzyl alcohols are readily nitrated with little or no oxidation (<4%) occurring. The addition of the iron catalyst activates the system to such an extent that nitration of an activated aromatic ring, such as toluene, occurs quantitatively at -100Β°C. This high activity allows compounds with sensitive functional groups such as alkenes to be smoothly nitrated.

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ChemInform Abstract: A Fast and Mild Met
ChemInform Abstract: A Fast and Mild Method for the Nitration of Aromatic Rings.
✍ Radoslaw R. Bak; Andrew J. Smallridge πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 28 KB πŸ‘ 2 views

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