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A false positive for clozapine using high-pressure liquid chromatography with ultraviolet detection

โœ Scribed by Unax Lertxundi; Margarita H. Manrique; Saioa D. Echaburu; Manuel Martinez

Book ID
114806996
Publisher
John Wiley and Sons
Year
2012
Tongue
Dutch
Weight
459 KB
Volume
24
Category
Article
ISSN
0924-2708

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โœ P. T. McCarthy; S. Hughes; C. Paton ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 579 KB

A simple method for the measurement of clozapine and its A'-desmethyl metabolite in human plasma or serum by high performance liquid chromatography is described. An internal standard (aqueous nortriptyline, 4 mg/L) (50 pL) and Tris buffer (2 mol/L, pH 10.6) (100 pL) are added to plasma/serum (200 pL