A facile, water mediated, microwave-assisted synthesis of 4,6-diaryl-2,3,3a,4-tetrahydro-1H-pyrido[3,2,1-jk]carbazoles by a domino Fischer indole reaction–intramolecular cyclization sequence
✍ Scribed by Chitra, Selvam; Paul, Nidhin; Muthusubramanian, Shanmugam; Manisankar, Paramasivam
- Book ID
- 120329618
- Publisher
- Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 387 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1463-9262
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📜 SIMILAR VOLUMES
A convenient procedure for preparation of the title compound of->99% ee starting from 1-(2,3-difluoro-6-nitrophenoxy)-2-propanone (3) is presented. The key reaction is the intramolecular cyclization reaction in the presence of zinc chloride.
Aryl-substituted tricarbonyl(rl4-cyclohexa -1,3-diene)iron complexes are oxidatively cyclized in protic medium in the air to tricarbonyliron-complexed 4a,9a-dihydro-9H-carbazoles. The method is applied to the total synthesis of mukonine and mukonidine.
Transition-Metal Complexes in Organic Synthesis. Part 36. Cyclization of Tricarbonyliron Complexes by Oxygen to 4a,9a-Dihydro-9Hcarbazoles: Application to the Synthesis of Mukonine, Mukonidine, and Pyrido(3,2,1-jk)carbazoles. -A novel method for the cyclization of aryl-substituted iron complexes su
## Abstract Triphenylphosphine (TPP) has been utilized as a novel and efficient catalyst for the Knoevenagel condensation of indole‐3‐carboxaldehydes **1(a–e)**, 1‐methyl‐1H‐indole‐3‐carboxaldehydes **4(a–e)**, and 1‐ethyl‐1H‐indole‐3‐carboxaldehydes **6(a–e)** with the active methylene compound, t