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A Facile Synthetic Method of Herbicidal 2,3-Dihydro-3-methylene-2-substituted-phenyl-1 H -isoindol-1-one Derivatives

โœ Scribed by Kim, Jae Nyoung; Ryu, Eung K.

Book ID
120665386
Publisher
Taylor and Francis Group
Year
1996
Tongue
English
Weight
246 KB
Volume
26
Category
Article
ISSN
0039-7911

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โœ Eric Deniau; Dieter Enders; Axel Couture; Pierre Grandclaudon ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 164 KB

A concise and efficient synthesis of highly enantioenriched 3-alkyl and 3-aryl-2,3-dihydro-1H-isoindolinones is reported. The key step relies on the diastereoselective reduction of the N-acylhydrazonium salts generated by acidic treatment of hemiaminal precursors bearing the (S)-2-methoxymethylpyrro