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A Facile Synthesis of the Major Urinary Metabolite of Metronidazole

✍ Scribed by Hambalek, Robert J.; Just, George


Book ID
120477360
Publisher
Taylor and Francis Group
Year
1993
Tongue
English
Weight
343 KB
Volume
23
Category
Article
ISSN
0039-7911

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πŸ“œ SIMILAR VOLUMES


Facile Syntheses of the Three Major Meta
✍ Ryanβ€…J. Morrow; Jeffβ€…S. Millership; Paulβ€…S. Collier πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 German βš– 172 KB

## Abstract Efficient, mild syntheses of the three major metabolites **2**–**4** of the important antipsychotic drug thioridazine (**1**) have been developed. The cardiotoxic metabolite **2** with a ring sulfoxide moiety was prepared in 96% yield by oxidation of **1** with NaIO~4~ under acidic cond