𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A facile synthesis of some thieno/furo-[2,3-d]pyrimidine-2-yl-thioacetic acid derivatives

✍ Scribed by S̨Eref Demirayak; Usama Abu Mohsen

Publisher
Journal of Heterocyclic Chemistry
Year
2001
Tongue
English
Weight
23 KB
Volume
38
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The reaction of 2‐(α‐chloroacetamido)‐3‐cyano‐4,5‐disubstituted thiophenes/furanes with ammonium thiocyanate in methanol or ethanol afforded methyl or ethyl (4‐amino‐5,6‐disubstituted thieno/furo[2,3‐d]‐pyrimidine‐2‐yl)thioacetates in good yields.

📜 SIMILAR VOLUMES

Nitriles in heterocyclic synthesis: A no
Nitriles in heterocyclic synthesis: A novel synthesis of some thieno[2,3-d]pyrimidine and thieno[2,3-b]pyridine derivatives
✍ Zaghloul El-Shahat Kandeel 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 344 KB 👁 2 views

## A simple route to the synthesis of the pharmaceutically important thieno[2,3-d]pyrimidine derivatives and of thieno[2,3-b]pyridine derivatives via the use of 5-amin0-3-phenylthiophene-2,Cdicarbonitrile (2) as a starting material is described.

Convenient synthesis of substituted 2-(2
Convenient synthesis of substituted 2-(2-iminocoumarin-3-yl)thieno[2,3-d]pyrimidin-4-ones
✍ Pavlo E. Shynkarenko; Sergiy V. Vlasov; Sergiy M. Kovalenko; Svitlana V. Shishki 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 185 KB 👁 1 views

## Abstract magnified image The interaction of both 2‐iminocoumarin‐3‐carbonitriles and 2‐iminocoumarin‐3‐carbothioamides with 2‐aminothiophen‐3‐carboxamides lead to formation of 3‐(4‐oxo‐3,4‐dihydrothieno[2,3‐__d__]pyrimidin‐2‐yl)‐2‐iminocoumarins in two steps. The simplicity of the procedure, as