A new synthesis of N-acetylneuraminic acid (NeuSAc; 28) via the aldehyde 10 is described. The aldehyde 10 was obtained from N-acetyl-o-glucosamine (11; 5 steps, overall yield ca. 6 %) or from o-glucono-1,s-lactone (17; 6 steps, overall yield ra. 57%). Thus, on the one hand, N-acetyl-D-mannosamine (1
β¦ LIBER β¦
A Facile Synthesis of N-Acetylneuraminic Acid Glycal.
β Scribed by Nadezhda Yu. Kulikova; Anna M. Shpirt; Leonid O. Kononov
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 16 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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