A facile synthesis of Enantiopure γ-Amino-And γ-Hydroxy-β-Ketosulfones
✍ Scribed by Sengupta, Saumitra; SenSarma, Debarati; Mondal, Somnath
- Book ID
- 120989297
- Publisher
- Taylor and Francis Group
- Year
- 1998
- Tongue
- English
- Weight
- 297 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0039-7911
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📜 SIMILAR VOLUMES
Starting from 'chiral-pool' derived "t-amino-13-ketosulfones, a facile synthesis of enantiopure a-amino ketones has been developed via an ct-alkylation-desulfonation sequence. Extension of this methodology to enantiopure et-acetoxy ketone synthesis,however, have met with limited success.
1998 ketones ketones (acyclic compounds) P 0200 ## 47 -080 γ-Amino-β-ketosulfones as Chiral Educts: A Facile Synthesis of Enantiopure α-Amino Ketones. -A new method for the preparation of enantiopure α-amino ketones, precursors of synthetically and pharmaceutically important β-amino alcohols, is
## Abstract Enantiopure (3__S__,4__R__)‐ and (3__S__,4__S__)‐3‐amino‐4‐hydroxyhexanoic acids and (4__S__,5__R__)‐ and (4__S__,5__S__)‐4‐amino‐5‐hydroxyheptanoic acid derivatives have been prepared by stereodivergent synthesis from L‐aspartic and L‐glutamic acids, respectively. The stereochemistry a