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A Facile Synthesis of cis-1-Methyl-1,2,3,3a,4,8b- hexahydropyrrolo[3,2-f]pyrindine, an Annulated Nicotine Analog

โœ Scribed by Zhai, Hongbin; Liu, Peng; Luo, Shengjun; Fang, ; Zhao, Mingyue

Book ID
111862119
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
35 KB
Volume
4
Category
Article
ISSN
1523-7060

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Synthesis of the 3a-(3-Indolyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3b]indole Core of Leptosins D-F. -The Fischer indole reaction of the previously reported L-tryptophan-derived aldehyde (I) with phenyl hydrazine in the presence of freshly fused zinc chloride provides the core unit (IV) of the leptosin