✦ LIBER ✦

A facile synthesis of ceramides

✍ Scribed by Yasuo Kishimoto

Publisher: Elsevier Science
Year: 1975
Tongue: English
Weight: 414 KB
Volume: 15
Category: Article
ISSN: 0009-3084
DOI: 10.1016/0009-3084(75)90029-8

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✦ Synopsis

A new simple procedure for the synthesis of ceramide from free fatty acid and sphingosine by oxidation-reduction condensation with triphenylphosphine and 2,2'-dipyridyldisulfide has been described. N-lignoceroyl and N-cerebronoyl sphingosine were synthesized with this procedure producing an overall yield of 74% from lignoceric acid and 64% from cerebronic acid.

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