A facile synthesis of benzyl 2-acetamido-6-O-acetyl-4-O-(6-O-acetyl-3,4-O-isopropylidene-β-d-galactopyranosyl)-2-deoxy-β- d-glucopyranoside, a key intermediate for the synthesis of O-α-l-fucopyranosyl-(1→2)-O-β-d-galactopyranosyl-(1→4)-O-[α-l-fucopyranosyl- (1→3)]-2-acetamido-2-deoxy-d-glucopyranose
✍ Scribed by Surjit S. Rana; Khushi L. Matta
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 269 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0008-6215
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📜 SIMILAR VOLUMES
Treatment of benzyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside with 4-methoxybenzaldehyde dimethyl acetal in N,N-dimethylformamide in the presence of 4-toluenesulfonic acid afforded the 4,6-O-(4-methoxybenzylidene) acetal, which was glycosylated with 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosy
Condensation of benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-a-D-galactopyranoside with 2,3,4-tri-o-acetyl-a-D-fucopyranosyl bromide in 1: 1 nitromethane-benzene, in the presence of powdered mercuric cyanide, afforded benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-0-(2,3,4-tri-O-acetyl-P-D-fucopyran