A facile synthesis of 7-halo-5H-indeno[1,2-b]pyridines and -pyridin-5-ones
โ Scribed by DuPriest, Mark T.; Schmidt, Charles L.; Kuzmich, Daniel; Williams, Stanly B.
- Book ID
- 127378519
- Publisher
- American Chemical Society
- Year
- 1986
- Tongue
- English
- Weight
- 429 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The highly reactive 1โ:โ1 intermediate generated in the reaction between dialkyl acetylenedicarboxylate (=butโ2โynedioic acid dialkyl ester) **4** and triphenylphosphine was trapped by 2โaminoโ4โoxoโ4__H__โ1โbenzopyranโ3โcarboxaldehydes **5** to yield highly functionalized dialkylโ1,5โd
Acetylation and benzoylation of oxazolo[4,5-b]pyridin-2(3H)-ones, 2-phenyloxazolo-[4,5-b]pyridines and pyrrolo[2,3-b]pyridin-2(2H)-ones were realised via reactions catalyzed with palladium.
## Abstract The title compounds 5aโc and 7aโm have been prepared by Vilsmeier formylation of 4โaminocoumarins 1 yielding aldehydes 2, and subsequent condensation of 2 with CโH acids in the presence of piperidine. This condensation probably proceeds via the intermediate ylidenemalonic esters 4. By m