A facile synthesis of 4-(sulfonylmethyl)indoles from 4-oxo-4,5,6,7-tetrahydroindole: Formal total synthesis of 6,7-secoagroclavine
β Scribed by Naoto Hatanaka; Osamu Ozaki; Masakatsu Matsumoto
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 264 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A general two-step procedure for the reduction of indoles to the corresponding 4,5,6,7-tetrahydroindoles has been developed. A regioselective Birch reduction followed by catalytic hydrogenation is employed to accomplish this transformation. Yields for the sensitive pyrrole products are typically bet
The 3-alkyl-4,5,6,7\_tetrahydroindoles 4a and 4b reacted with -lead tetraacetate in acetic acid to give the corresponding 7acetoxy derivatives; hydrolysis, followed by treatment with potassium ferricyanide in refluxing acetic acid afforded the novel porphyrins 6a and 6b. --Recently o variety of nick