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Synthesis of porphyrins with four exocyclic rings from 4,5,6,7-tetrahydroindoles

✍ Scribed by Timothy D Lash; Karla A Bladel; Marty C Johnson

Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
203 KB
Volume
28
Category
Article
ISSN
0040-4039

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✦ Synopsis

The 3-alkyl-4,5,6,7_tetrahydroindoles 4a and 4b reacted with -lead tetraacetate in acetic acid to give the corresponding 7acetoxy derivatives; hydrolysis, followed by treatment with potassium ferricyanide in refluxing acetic acid afforded the novel porphyrins 6a and 6b. --Recently o variety of nickel and vanadyl porphyrins have been isolated from 10.

Analytical data could not be obtained for lo, although the stable methoxy 12a and ethoxy 12b derivatives gave satisfactory CHN Analyses.

πŸ“œ SIMILAR VOLUMES

Reduction of the indole ring system: syn
Reduction of the indole ring system: synthesis of 4,5,6,7-tetrahydroindoles
✍ Casey C. McComas; David L. Van Vranken πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 250 KB

A general two-step procedure for the reduction of indoles to the corresponding 4,5,6,7-tetrahydroindoles has been developed. A regioselective Birch reduction followed by catalytic hydrogenation is employed to accomplish this transformation. Yields for the sensitive pyrrole products are typically bet