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A facile synthesis of 3-alkoxy phthalides by the palladium catalyzed carbonylative cyclization of o-bromobenzaldehyde

โœ Scribed by Sang Chul Shim; Dong Yub Lee; Li Hong Jiang; Tae Jeong Kim; Sung-Dong Cho


Book ID
112131173
Publisher
Journal of Heterocyclic Chemistry
Year
1995
Tongue
English
Weight
219 KB
Volume
32
Category
Article
ISSN
0022-152X

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๐Ÿ“œ SIMILAR VOLUMES


Synthesis of 3-phenoxy-1,3-dihydro-1-iso
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## Abstract 2โ€Bromobenzaldehyde reacts with phenols in acetonitrile under carbon monoxide pressure in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride to afford the corresponding 3โ€phenoxyโ€1,3โ€dihydroโ€1โ€isobenzofuranones in high yields.

Palladium-catalyzed synthesis of 3-(alky
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## Abstract 2โ€Bromobenzaldehyde reacts with an excess of primary amines under a carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3โ€(alkylamino)isoindolinโ€1โ€ones in good yields.