A facile synthesis of 3-alkoxy phthalides by the palladium catalyzed carbonylative cyclization of o-bromobenzaldehyde
โ Scribed by Sang Chul Shim; Dong Yub Lee; Li Hong Jiang; Tae Jeong Kim; Sung-Dong Cho
- Book ID
- 112131173
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1995
- Tongue
- English
- Weight
- 219 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-152X
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๐ SIMILAR VOLUMES
## Abstract 2โBromobenzaldehyde reacts with phenols in acetonitrile under carbon monoxide pressure in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride to afford the corresponding 3โphenoxyโ1,3โdihydroโ1โisobenzofuranones in high yields.
## Abstract 2โBromobenzaldehyde reacts with an excess of primary amines under a carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3โ(alkylamino)isoindolinโ1โones in good yields.