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A facile synthesis of 2,3-disubstituted pyrrolo[2,3-b]pyridines via palladium-catalyzed heteroannulation with internal alkynes

โœ Scribed by Sang Sun Park; Joong-Kwon Choi; Eul Kgun Yum; Deok-Chan Ha

Book ID
108386436
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
229 KB
Volume
39
Category
Article
ISSN
0040-4039

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Synthesis of 1,2,3-trisubstituted pyrrol
Synthesis of 1,2,3-trisubstituted pyrrolo[3,2-c]quinolines via palladium-catalyzed heteroannulation with internal alkynes
โœ Seung Kyu Kang; Sang Sun Park; Sung Soo Kim; Joong-Kwon Choi; Eul Kgun Yum ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 210 KB

Various 1,2, quinolines were synthesized by palladium-catalyzed heteroannulation of 4-amino-3-iodoquinoline derivatives and internal alkynes. The 1,2,3-trisubstituted pyrrolo[3,2-c]quinolines could be further transformed by desilylation, debenzylation, or substitution.