A facile synthesis of 2-aminothiazolo[5,4-b]- and 2-aminothiazolo[4,5-c] pyridines
β Scribed by Henry W. Aitland; Gary A. Molander
- Book ID
- 111887780
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1977
- Tongue
- English
- Weight
- 329 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0022-152X
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π SIMILAR VOLUMES
Convenient synthesis of 4-substituted 2-aminothiazolo [4,5-d]pyridazinones has been achieved in 12 steps with overall yield of 19% by employing Grignard reaction as the key step. The route utilizes well established thiazole ring formation followed by Grignard reaction to introduce substitution at 4-
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