A facile, general route to perfluoroalkyl allenes
β Scribed by Donald J. Burton; Greg A. Hartgraves; Jeffrey Hsu
- Book ID
- 104228705
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 203 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
Perfluoroalkyl copper reagents react with propargyl halides or tosylates in DMF or DMSO at 0Β°CRT to afford perfluoroalkyl allenes regiospecifically in good yield.
π SIMILAR VOLUMES
Grignard reagents react with 7-oxabicycloC2.2.llhept-5-ene-2,3-dicarboxylic anhydride and produce in high yields the corresponding substituted bicycle-y-butanolides. These lactones produce the title compounds by retro Diels-Alder reaction during distillation. Previously, we have demonstrated that th
Ketone2 undergoes Knoevenagel condensation with five malonic derivatives\_7, yielding, ufter flash-thermolysis, the gem-&activated alLenes l-5 in 20-50 % yields. \_-The synthetic utility and ketene equivalence of allenes gem-disubstituted by electroattracting groups, in nucleophilic additions and (2