In spite of the current interest in the highly strained bicyclo[2.l.llhexane system, there is no efficient, non-photochemical synthesis of this system from readily available compounds.
A facile entry into the benzo[7,8] bicyclo[4.2.1]nonane system
✍ Scribed by R.C. Hahn; R.P. Johnson
- Publisher
- Elsevier Science
- Year
- 1973
- Tongue
- French
- Weight
- 187 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0040-4039
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**Facile synthesis of derivatives of 2,4‐diphenyl‐3‐azabicyclo[3.3.1]nonane and 7,9‐diphenyl‐8‐azabicyclo[4.3.1]decane** The facile synthesis of hydantoins, cyanhydrins and aminonitriles derived from 2,4‐diphenyl‐3‐azabicyclo[3.3.1]nonanone and 7,9‐diphenyl‐8‐azabicyclo[4.3.1]decanone is described.
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A Facile Entry into the Ring System of Sativene. -Careful bromination of the diketone (I) allows the synthesis of the dibromides (II) and (III) or corresponding tribromide (IV). Their DBU-mediated dehydrobromination leads to tricyclic compounds of which (V) and (VII) have the same carbon skeleton a