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A facile approach to the synthesis of 3,4-disubstituted-2-aminothiazolium derivatives through the use of a ‘volatilizable’ support

✍ Scribed by Yangmei Li; Marc Giulianotti; Richard A. Houghten

Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
190 KB
Volume
51
Category
Article
ISSN
0040-4039

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✦ Synopsis

A facile solid-phase synthetic approach to the synthesis of 3,4-disubstituted-2-aminothiazolium derivatives was reported. Functionalized aminomethylphenyl silica gel was used as a 'volatilizable' support. The products were cleaved with 10% HF and were obtained in high yields and purities.

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