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A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas

✍ Scribed by Phioanh Leia Nghiemphu, Albert Lai, Richard M. Green, David A. Reardon, Timothy Cloughesy


Book ID
118807108
Publisher
Springer US
Year
2012
Tongue
English
Weight
194 KB
Volume
110
Category
Article
ISSN
0167-594X

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## Abstract ## BACKGROUND Although temozolomide is active against recurrent malignant glioma, responses in many patients are modest and short‐lived. Temozolomide may prove more effective in combination with other agents. Therefore, combination oral chemotherapy for these patients is a particularly