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A Divergent Synthesis of 1,8-Naphthyridines and Hydropyridopyrimidinones by the Reactions of o -Aminonitriles with Ketones

✍ Scribed by Yang, Liupan; Li, Jiarong; Chai, Hongxin; Lu, Hongyan; Zhang, Qi; Shi, Daxin


Book ID
120264960
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
741 KB
Volume
31
Category
Article
ISSN
0256-7660

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Synthesis of 2,4,8-Trisubstituted 1,7-Na
✍ Kazuhiro Kobayashi; Taketoshi Kozuki; Shuhei Fukamachi; Hisatoshi Konishi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 German ⚖ 153 KB

## Abstract A convenient method for the synthesis of 2,4,8‐trisubstituted 1,7‐naphthyridines **6** by the reaction of (__E__)‐4‐(1‐aryl‐2‐methoxyethenyl)‐3‐isocyanopyridines **4**, which could be easily prepared from commercially available 3‐aminopyridine __via__ aroylation of lithium (4‐lithiopyri